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Angelica Polysaccharide Antagonizes 5-FU-Induced Oxidative Stress Injury to Reduce Apoptosis in the Liver Through Nrf2 Pathway

Oxidative stress induced by chemotherapeutic agents causes hepatotoxicity. 5-Fluorouracil (5-FU) has been found to have a variety of side effects, but its toxic effect on the liver and the mechanism are still unclear. Angelica polysaccharide (ASP), the main active ingredient of Dang Gui, has antioxi...

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Detalles Bibliográficos
Autores principales: Zeng, Di, Wang, Yaping, Chen, Yi, Li, Danyang, Li, Guoli, Xiao, Hanxianzhi, Hou, Jiyin, Wang, Ziling, Hu, Ling, Wang, Lu, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415481/
https://www.ncbi.nlm.nih.gov/pubmed/34485154
http://dx.doi.org/10.3389/fonc.2021.720620