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Pharmacokinetics and Pharmacodynamics of a Novel Virulent Klebsiella Phage Kp_Pokalde_002 in a Mouse Model

Phage therapy is one of the most promising alternatives to antibiotics as we face global antibiotic resistance crisis. However, the pharmacokinetics (PK) and pharmacodynamics (PD) of phage therapy are largely unknown. In the present study, we aimed to evaluate the PK/PD of a locally isolated virulen...

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Detalles Bibliográficos
Autores principales: Dhungana, Gunaraj, Nepal, Roshan, Regmi, Madhav, Malla, Rajani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415502/
https://www.ncbi.nlm.nih.gov/pubmed/34485172
http://dx.doi.org/10.3389/fcimb.2021.684704