6β-Hydroxytestosterone Promotes Angiotensin II-Induced Hypertension via Enhanced Cytosolic Phospholipase A(2)α Activity

This study was conducted to test the hypothesis that the CYP1B1 (cytochrome P450 1B1)-testosterone metabolite 6β-hydroxytestosterone contributes to angiotensin II-induced hypertension by promoting activation of group IV cPLA(2)α (cytosolic phospholipase A(2)α) and generation of prohypertensive eicos...

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Detalles Bibliográficos
Autores principales: Singh, Purnima, Song, Chi Young, Dutta, Shubha R., Pingili, Ajeeth, Shin, Ji Soo, Gonzalez, Frank J., Bonventre, Joseph V., Malik, Kafait U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415516/
https://www.ncbi.nlm.nih.gov/pubmed/34420370
http://dx.doi.org/10.1161/HYPERTENSIONAHA.121.17927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415516/
https://www.ncbi.nlm.nih.gov/pubmed/34420370
http://dx.doi.org/10.1161/HYPERTENSIONAHA.121.17927

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