Development of an Antibiotic Resistance Breaker to Resensitize Drug-Resistant Staphylococcus aureus: In Silico and In Vitro Approach

Efflux pumps are one of the predominant microbial resistant mechanisms leading to the development of multidrug resistance. In Staphylococcus aureus, overexpression of NorA protein enables the efflux of antibiotics belonging to the class of fluoroquinolones and, thus, makes S. aureus resistant. Hence...

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Detalles Bibliográficos
Autores principales: Thamilselvan, Gopalakrishnan, Sarveswari, Hema Bhagavathi, Vasudevan, Sahana, Stanley, Alex, Shanmugam, Karthi, Vairaprakash, Pothiappan, Solomon, Adline Princy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415528/
https://www.ncbi.nlm.nih.gov/pubmed/34485178
http://dx.doi.org/10.3389/fcimb.2021.700198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415528/
https://www.ncbi.nlm.nih.gov/pubmed/34485178
http://dx.doi.org/10.3389/fcimb.2021.700198

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