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NAD(+) Degrading Enzymes, Evidence for Roles During Infection
Declines in cellular nicotinamide adenine dinucleotide (NAD) contribute to metabolic dysfunction, increase susceptibility to disease, and occur as a result of pathogenic infection. The enzymatic cleavage of NAD(+) transfers ADP-ribose (ADPr) to substrate proteins generating mono-ADP-ribose (MAR), po...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415550/ https://www.ncbi.nlm.nih.gov/pubmed/34485381 http://dx.doi.org/10.3389/fmolb.2021.697359 |