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NAD(+) Degrading Enzymes, Evidence for Roles During Infection

Declines in cellular nicotinamide adenine dinucleotide (NAD) contribute to metabolic dysfunction, increase susceptibility to disease, and occur as a result of pathogenic infection. The enzymatic cleavage of NAD(+) transfers ADP-ribose (ADPr) to substrate proteins generating mono-ADP-ribose (MAR), po...

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Detalles Bibliográficos
Autores principales: Tan, Arnold, Doig, Craig L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415550/
https://www.ncbi.nlm.nih.gov/pubmed/34485381
http://dx.doi.org/10.3389/fmolb.2021.697359