Inhibition of Fatty Acid Synthesis Aggravates Brain Injury, Reduces Blood-Brain Barrier Integrity and Impairs Neurological Recovery in a Murine Stroke Model

Inhibition of fatty acid synthesis (FAS) stimulates tumor cell death and reduces angiogenesis. When SH-SY5Y cells or primary neurons are exposed to hypoxia only, inhibition of FAS yields significantly enhanced cell injury. The pathophysiology of stroke, however, is not only restricted to hypoxia but...

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Detalles Bibliográficos
Autores principales: Janssen, Lisa, Ai, Xiaoyu, Zheng, Xuan, Wei, Wei, Caglayan, Ahmet B., Kilic, Ertugrul, Wang, Ya-chao, Hermann, Dirk M., Venkataramani, Vivek, Bähr, Mathias, Doeppner, Thorsten R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415573/
https://www.ncbi.nlm.nih.gov/pubmed/34483846
http://dx.doi.org/10.3389/fncel.2021.733973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415573/
https://www.ncbi.nlm.nih.gov/pubmed/34483846
http://dx.doi.org/10.3389/fncel.2021.733973

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