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miQC: An adaptive probabilistic framework for quality control of single-cell RNA-sequencing data
Single-cell RNA-sequencing (scRNA-seq) has made it possible to profile gene expression in tissues at high resolution. An important preprocessing step prior to performing downstream analyses is to identify and remove cells with poor or degraded sample quality using quality control (QC) metrics. Two w...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415599/ https://www.ncbi.nlm.nih.gov/pubmed/34428202 http://dx.doi.org/10.1371/journal.pcbi.1009290 |