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Emergence of a KPC Variant Conferring Resistance to Ceftazidime-Avibactam in a Widespread ST11 Carbapenem-Resistant Klebsiella pneumoniae Clone in China

Carbapenem-resistant Klebsiella pneumoniae (CRKP) infection poses a great threat to public health worldwide, and KPC-2-producing strains are the main factors responsible for resistance to carbapenems in China. Ceftazidime/avibactam (CZA) is a novel β-lactam/β-lactamase inhibitor combination with goo...

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Detalles Bibliográficos
Autores principales: Li, Xi, Quan, Jingjing, Ke, Huanhuan, Wu, Wenhao, Feng, Yu, Yu, Yunsong, Jiang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415713/
https://www.ncbi.nlm.nih.gov/pubmed/34484166
http://dx.doi.org/10.3389/fmicb.2021.724272