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Solution NMR of Nanoparticles in Serum: Protein Competition Influences Binding Thermodynamics and Kinetics

The spontaneous formation of a protein corona on a nanoparticle surface influences the physiological success or failure of the synthetic nanoparticle as a drug carrier or imaging agent used in vivo. A quantitative understanding of protein-nanoparticle interactions is therefore critical for the devel...

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Detalles Bibliográficos
Autores principales: Xu, Joanna Xiuzhu, Fitzkee, Nicholas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415878/
https://www.ncbi.nlm.nih.gov/pubmed/34483968
http://dx.doi.org/10.3389/fphys.2021.715419