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Risk Stratification of Cytogenetically Normal Acute Myeloid Leukemia With Biallelic CEBPA Mutations Based on a Multi-Gene Panel and Nomogram Model

BACKGROUND: Approximately 30% of Chinese individuals with cytogenetically normal acute myeloid leukemia (CN-AML) have biallelic CEBPA (biCEBPA) mutations. The prognosis and optimal therapy for these patients are controversial in clinical practice. METHODS: In this study, we performed targeted region...

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Detalles Bibliográficos
Autores principales: Wu, Li-Xin, Jiang, Hao, Chang, Ying-Jun, Zhou, Ya-Lan, Wang, Jing, Wang, Zi-Long, Cao, Lei-Ming, Li, Jin-Lan, Sun, Qiu-Yu, Cao, Shan-Bo, Lou, Feng, Zhou, Tao, Liu, Li-Xia, Wang, Cheng-Cheng, Wang, Yu, Jiang, Qian, Xu, Lan-Ping, Zhang, Xiao-Hui, Liu, Kai-Yan, Huang, Xiao-Jun, Ruan, Guo-Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415912/
https://www.ncbi.nlm.nih.gov/pubmed/34485141
http://dx.doi.org/10.3389/fonc.2021.706935