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Activation of STING Pathway Contributed to Cisplatin-Induced Cardiac Dysfunction via Promoting the Activation of TNF-α-AP-1 Signal Pathway

Cardiovascular complications are a well-documented limitation of conventional cancer chemotherapy. As a notable side effect of cisplatin, cardiotoxicity represents a major obstacle to the treatment of cancer. Recently, it has been reported that cyclic GMP-AMP synthase (cGAS) stimulator of interferon...

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Detalles Bibliográficos
Autores principales: Wang, Lintao, Zhang, Suya, Han, Jibo, Nie, Xiaoyan, Qi, Yajun, Han, Yingying, Chen, Xiong, He, Chaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415915/
https://www.ncbi.nlm.nih.gov/pubmed/34483919
http://dx.doi.org/10.3389/fphar.2021.711238