Deficiency of Intellectual Disability-Related Gene Brpf1 Attenuated Hippocampal Excitatory Synaptic Transmission and Impaired Spatial Learning and Memory Ability

Patients with monoallelic bromodomain and PHD finger-containing protein 1 (BRPF1) mutations showed intellectual disability. The hippocampus has essential roles in learning and memory. Our previous work indicated that Brpf1 was specifically and strongly expressed in the hippocampus from the perinatal...

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Detalles Bibliográficos
Autores principales: Xian, Weiwei, Cao, Jingli, Yuan, Xiangshan, Wang, Guoxiang, Jin, Qiuyan, Zhang, Hang, Zhou, Guomin, You, Linya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415984/
https://www.ncbi.nlm.nih.gov/pubmed/34485298
http://dx.doi.org/10.3389/fcell.2021.711792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415984/
https://www.ncbi.nlm.nih.gov/pubmed/34485298
http://dx.doi.org/10.3389/fcell.2021.711792

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