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Characterization of the ABC methionine transporter from Neisseria meningitidis reveals that lipidated MetQ is required for interaction

NmMetQ is a substrate-binding protein (SBP) from Neisseria meningitidis that has been identified as a surface-exposed candidate antigen for meningococcal vaccines. However, this location for NmMetQ challenges the prevailing view that SBPs in Gram-negative bacteria are localized to the periplasmic sp...

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Detalles Bibliográficos
Autores principales: Sharaf, Naima G, Shahgholi, Mona, Kim, Esther, Lai, Jeffrey Y, VanderVelde, David G, Lee, Allen T, Rees, Douglas C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416018/
https://www.ncbi.nlm.nih.gov/pubmed/34409939
http://dx.doi.org/10.7554/eLife.69742