LIN37-DREAM prevents DNA end resection and homologous recombination at DNA double-strand breaks in quiescent cells

DNA double-strand break (DSB) repair by homologous recombination (HR) is thought to be restricted to the S- and G(2)- phases of the cell cycle in part due to 53BP1 antagonizing DNA end resection in G(1)-phase and non-cycling quiescent (G(0)) cells. Here, we show that LIN37, a component of the DREAM...

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Detalles Bibliográficos
Autores principales: Chen, Bo-Ruei, Wang, Yinan, Tubbs, Anthony, Zong, Dali, Fowler, Faith C, Zolnerowich, Nicholas, Wu, Wei, Bennett, Amelia, Chen, Chun-Chin, Feng, Wendy, Nussenzweig, Andre, Tyler, Jessica K, Sleckman, Barry P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416021/
https://www.ncbi.nlm.nih.gov/pubmed/34477552
http://dx.doi.org/10.7554/eLife.68466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416021/
https://www.ncbi.nlm.nih.gov/pubmed/34477552
http://dx.doi.org/10.7554/eLife.68466

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