Cargando…

LIN37-DREAM prevents DNA end resection and homologous recombination at DNA double-strand breaks in quiescent cells

DNA double-strand break (DSB) repair by homologous recombination (HR) is thought to be restricted to the S- and G(2)- phases of the cell cycle in part due to 53BP1 antagonizing DNA end resection in G(1)-phase and non-cycling quiescent (G(0)) cells. Here, we show that LIN37, a component of the DREAM...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Bo-Ruei, Wang, Yinan, Tubbs, Anthony, Zong, Dali, Fowler, Faith C, Zolnerowich, Nicholas, Wu, Wei, Bennett, Amelia, Chen, Chun-Chin, Feng, Wendy, Nussenzweig, Andre, Tyler, Jessica K, Sleckman, Barry P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416021/ https://www.ncbi.nlm.nih.gov/pubmed/34477552 http://dx.doi.org/10.7554/eLife.68466

Ejemplares similares

DNA-PK promotes DNA end resection at DNA double strand breaks in G(0) cells
por: Fowler, Faith C, et al.
Publicado: (2022)

The regulation of DNA end resection by chromatin response to DNA double strand breaks
por: Chen, Bo-Ruei, et al.
Publicado: (2022)

Role of 53BP1 in end protection and DNA synthesis at DNA breaks
por: Paiano, Jacob, et al.
Publicado: (2021)

A Proximity Ligation Method to Detect Proteins Bound to Single-Stranded DNA after DNA End Resection at DNA Double-Strand Breaks
por: Fowler, Faith C., et al.
Publicado: (2021)

A Role for the Malignant Brain Tumour (MBT) Domain Protein LIN-61 in DNA Double-Strand Break Repair by Homologous Recombination
por: Johnson, Nicholas M., et al.
Publicado: (2013)

The DREAM complex through its subunit Lin37 cooperates with Rb to initiate quiescence
por: Mages, Christina FS, et al.
Publicado: (2017)

The Role of DNA Double-Strand Breaks in Spontaneous Homologous Recombination in S. cerevisiae
por: Lettier, Gaëlle, et al.
Publicado: (2006)

Phosphorylation of Histone H2B at DNA Double-Strand Breaks
por: Fernandez-Capetillo, Oscar, et al.
Publicado: (2004)

Optimizing the DNA Donor Template for Homology-Directed Repair of Double-Strand Breaks
por: Song, Fei, et al.
Publicado: (2017)

PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks
por: Alonso-de Vega, Ignacio, et al.
Publicado: (2020)

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks
por: Bolderson, Emma, et al.
Publicado: (2010)

Homologous recombination repair is essential for repair of vosaroxin-induced DNA double-strand breaks
por: Hawtin, Rachael Elizabeth, et al.
Publicado: (2010)

DNA double-strand breaks alter the spatial arrangement of homologous loci in plant cells
por: Hirakawa, Takeshi, et al.
Publicado: (2015)

DNA double-strand break repair in Penaeus monodon is predominantly dependent on homologous recombination
por: Srivastava, Shikha, et al.
Publicado: (2017)

CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair
por: Hilmi, Khalid, et al.
Publicado: (2017)

The Role of Drosophila CtIP in Homology-Directed Repair of DNA Double-Strand Breaks
por: Yannuzzi, Ian, et al.
Publicado: (2021)

BRD4 promotes resection and homology-directed repair of DNA double-strand breaks
por: Barrows, John K., et al.
Publicado: (2022)

Restrictions Limiting the Generation of DNA Double Strand Breaks during Chromosomal V(D)J Recombination
por: Tillman, Robert E., et al.
Publicado: (2002)

Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks
por: Dong, Jun, et al.
Publicado: (2017)

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair
por: Abdou, Ismail, et al.
Publicado: (2015)

The RNF8 and RNF168 Ubiquitin Ligases Regulate Pro- and Anti-Resection Activities at Broken DNA Ends During Non-Homologous End Joining
por: Chen, Bo-Ruei, et al.
Publicado: (2021)

Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break
por: Wang, Pingping, et al.
Publicado: (2017)

Role of the silkworm argonaute2 homolog gene in double-strand break repair of extrachromosomal DNA
por: Tsukioka, Haruna, et al.
Publicado: (2006)

Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin
por: Manova, Vasilissa, et al.
Publicado: (2012)

A Lamin-Binding Ligand Inhibits Homologous Recombination Repair of DNA Double-Strand Breaks
por: Li, Bingbing X., et al.
Publicado: (2018)

Chromosome Preference During Homologous Recombination Repair of DNA Double-Strand Breaks in Drosophila melanogaster
por: Fernandez, Joel, et al.
Publicado: (2019)

One end to rule them all: Non-homologous end-joining and homologous recombination at DNA double-strand breaks
por: Ensminger, Michael, et al.
Publicado: (2020)

MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks
por: Helmink, Beth A., et al.
Publicado: (2009)

Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair
por: Kalasova, Ilona, et al.
Publicado: (2020)

Non-Homologous End Joining and Homology Directed DNA Repair Frequency of Double-Stranded Breaks Introduced by Genome Editing Reagents
por: Zaboikin, Michail, et al.
Publicado: (2017)

Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
por: Kruhlak, Michael J., et al.
Publicado: (2006)

RB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1
por: Vélez-Cruz, Renier, et al.
Publicado: (2016)

DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining
por: Head, PamelaSara E, et al.
Publicado: (2023)

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
por: Beucher, Andrea, et al.
Publicado: (2009)

Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation
por: Groth, Petra, et al.
Publicado: (2012)

Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination
por: Gao, Min, et al.
Publicado: (2014)

Pyruvate kinase M2 regulates homologous recombination-mediated DNA double-strand break repair
por: Sizemore, Steven T., et al.
Publicado: (2018)

Sycp1 Is Not Required for Subtelomeric DNA Double-Strand Breaks but Is Required for Homologous Alignment in Zebrafish Spermatocytes
por: Imai, Yukiko, et al.
Publicado: (2021)

Mitotic cells can repair DNA double-strand breaks via a homology-directed pathway
por: Sakamoto, Yuki, et al.
Publicado: (2020)

The Safe Path at the Fork: Ensuring Replication-Associated DNA Double-Strand Breaks are Repaired by Homologous Recombination
por: Nickoloff, Jac A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ul310rli5es8iocg47udm3afoh