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Haplotype-Specific Expression Analysis of MHC Class II Genes in Healthy Individuals and Rheumatoid Arthritis Patients

HLA-DRB1 alleles have been associated with several autoimmune diseases. For anti-citrullinated protein antibody positive rheumatoid arthritis (RA), HLA-DRB1 shared epitope (SE) alleles are the major genetic risk factors. In order to study the genetic regulation of major histocompatibility complex (M...

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Detalles Bibliográficos
Autores principales: Houtman, Miranda, Hesselberg, Espen, Rönnblom, Lars, Klareskog, Lars, Malmström, Vivianne, Padyukov, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416041/
https://www.ncbi.nlm.nih.gov/pubmed/34484204
http://dx.doi.org/10.3389/fimmu.2021.707217