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PopCover-2.0. Improved Selection of Peptide Sets With Optimal HLA and Pathogen Diversity Coverage

The use of minimal peptide sets offers an appealing alternative for design of vaccines and T cell diagnostics compared to conventional whole protein approaches. T cell immunogenicity towards peptides is contingent on binding to human leukocyte antigen (HLA) molecules of the given individual. HLA is...

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Detalles Bibliográficos
Autores principales: Nilsson, Jonas Birkelund, Grifoni, Alba, Tarke, Alison, Sette, Alessandro, Nielsen, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416060/
https://www.ncbi.nlm.nih.gov/pubmed/34484239
http://dx.doi.org/10.3389/fimmu.2021.728936