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PopCover-2.0. Improved Selection of Peptide Sets With Optimal HLA and Pathogen Diversity Coverage
The use of minimal peptide sets offers an appealing alternative for design of vaccines and T cell diagnostics compared to conventional whole protein approaches. T cell immunogenicity towards peptides is contingent on binding to human leukocyte antigen (HLA) molecules of the given individual. HLA is...
Autores principales: | Nilsson, Jonas Birkelund, Grifoni, Alba, Tarke, Alison, Sette, Alessandro, Nielsen, Morten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416060/ https://www.ncbi.nlm.nih.gov/pubmed/34484239 http://dx.doi.org/10.3389/fimmu.2021.728936 |
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