Stochastic Model of the Adaptive Immune Response Predicts Disease Severity and Captures Enhanced Cross-Reactivity in Natural Dengue Infections

The dengue virus circulates as four distinct serotypes, where a single serotype infection is typically asymptomatic and leads to acquired immunity against that serotype. However, the developed immunity to one serotype is thought to underlie the severe manifestation of the disease observed in subsequ...

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Detalles Bibliográficos
Autores principales: Nguyen, Hung D., Chaudhury, Sidhartha, Waickman, Adam T., Friberg, Heather, Currier, Jeffrey R., Wallqvist, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416063/
https://www.ncbi.nlm.nih.gov/pubmed/34484195
http://dx.doi.org/10.3389/fimmu.2021.696755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416063/
https://www.ncbi.nlm.nih.gov/pubmed/34484195
http://dx.doi.org/10.3389/fimmu.2021.696755

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