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The Role of Mitochondrial DNA Variation in Drug Response: A Systematic Review

Background: The triad of drug efficacy, toxicity and resistance underpins the risk-benefit balance of all therapeutics. The application of pharmacogenomics has the potential to improve the risk-benefit balance of a given therapeutic via the stratification of patient populations based on DNA variants...

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Detalles Bibliográficos
Autores principales: Jones, Samantha W., Ball, Amy L., Chadwick, Amy E., Alfirevic, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416105/
https://www.ncbi.nlm.nih.gov/pubmed/34484295
http://dx.doi.org/10.3389/fgene.2021.698825