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The Role of Mitochondrial DNA Variation in Drug Response: A Systematic Review
Background: The triad of drug efficacy, toxicity and resistance underpins the risk-benefit balance of all therapeutics. The application of pharmacogenomics has the potential to improve the risk-benefit balance of a given therapeutic via the stratification of patient populations based on DNA variants...
Autores principales: | Jones, Samantha W., Ball, Amy L., Chadwick, Amy E., Alfirevic, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416105/ https://www.ncbi.nlm.nih.gov/pubmed/34484295 http://dx.doi.org/10.3389/fgene.2021.698825 |
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