Calcium chelator BAPTA-AM protects against iron overload-induced chondrocyte mitochondrial dysfunction and cartilage degeneration

Osteoarthritis (OA) is a common joint disease that is characterized by cartilage degradation. Iron deposition in the joints is common during the pathogenic progression of OA and recent studies have indicated that iron overload is an important contributor to OA progression. Calcium chelators have bee...

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Detalles Bibliográficos
Autores principales: Jing, Xingzhi, Wang, Qiang, Du, Ting, Zhang, Weimin, Liu, Xiaoyang, Liu, Qiang, Li, Tao, Wang, Guodong, Chen, Feifei, Cui, Xingang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416145/
https://www.ncbi.nlm.nih.gov/pubmed/34468013
http://dx.doi.org/10.3892/ijmm.2021.5029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416145/
https://www.ncbi.nlm.nih.gov/pubmed/34468013
http://dx.doi.org/10.3892/ijmm.2021.5029

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