Pacbio Sequencing of PLC/PRF/5 Cell Line and Clearance of HBV Integration Through CRISPR/Cas-9 System

The integration of HBV DNA is one of the carcinogenic mechanisms of HBV. The clearance of HBV integration in hepatocyte is of great significance to cure chronic HBV infection and thereby prevent the occurrence of HBV-related hepatocellular carcinoma (HCC). However, the low throughput of traditional...

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Detalles Bibliográficos
Autores principales: Chen, Chia-Chen, Guan, Guiwen, Qi, Xuewei, Abulaiti, Abudurexiti, Zhang, Ting, Liu, Jia, Lu, Fengmin, Chen, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416172/
https://www.ncbi.nlm.nih.gov/pubmed/34485380
http://dx.doi.org/10.3389/fmolb.2021.676957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416172/
https://www.ncbi.nlm.nih.gov/pubmed/34485380
http://dx.doi.org/10.3389/fmolb.2021.676957

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