Cargando…

Pacbio Sequencing of PLC/PRF/5 Cell Line and Clearance of HBV Integration Through CRISPR/Cas-9 System

The integration of HBV DNA is one of the carcinogenic mechanisms of HBV. The clearance of HBV integration in hepatocyte is of great significance to cure chronic HBV infection and thereby prevent the occurrence of HBV-related hepatocellular carcinoma (HCC). However, the low throughput of traditional...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Chia-Chen, Guan, Guiwen, Qi, Xuewei, Abulaiti, Abudurexiti, Zhang, Ting, Liu, Jia, Lu, Fengmin, Chen, Xiangmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416172/ https://www.ncbi.nlm.nih.gov/pubmed/34485380 http://dx.doi.org/10.3389/fmolb.2021.676957

Ejemplares similares

Structural and functional characterization of Cas2 of CRISPR-Cas subtype I-C lacking the CRISPR component
por: Anand, Vineet, et al.
Publicado: (2022)

Downregulation of CacyBP by CRISPR/dCas9-KRAB Prevents Bladder Cancer Progression
por: Zheng, Hanxiong, et al.
Publicado: (2021)

A Small RNA Is Linking CRISPR–Cas and Zinc Transport
por: Märkle, Pascal, et al.
Publicado: (2021)

CRISPR Cas13-Based Tools to Track and Manipulate Endogenous Telomeric Repeat-Containing RNAs in Live Cells
por: Xu, Meng, et al.
Publicado: (2022)

Advances in the application of CRISPR-Cas technology in rapid detection of pathogen nucleic acid
por: Li, Xiaoping, et al.
Publicado: (2023)

The Influence of Copy-Number of Targeted Extrachromosomal Genetic Elements on the Outcome of CRISPR-Cas Defense
por: Severinov, Konstantin, et al.
Publicado: (2016)

Bio-Layer Interferometry Analysis of the Target Binding Activity of CRISPR-Cas Effector Complexes
por: Müller-Esparza, Hanna, et al.
Publicado: (2020)

Spontaneous Embedding of DNA Mismatches Within the RNA:DNA Hybrid of CRISPR-Cas9
por: Mitchell, Brandon P., et al.
Publicado: (2020)

CRISPR/dCas9-Mediated Parkin Inhibition Impairs Mitophagy and Aggravates Apoptosis of Rat Nucleus Pulposus Cells Under Oxidative Stress
por: Lan, Tao, et al.
Publicado: (2021)

A Blue Light-Inducible CRISPR-Cas9 System for Inhibiting Progression of Melanoma Cells
por: Wu, Xia, et al.
Publicado: (2020)

From DNA-protein interactions to the genetic circuit design using CRISPR-dCas systems
por: Shaytan, A. K., et al.
Publicado: (2022)

Can CRISPR/Cas Technology Be a Felicitous Stratagem Against the COVID-19 Fiasco? Prospects and Hitches
por: Konwarh, Rocktotpal
Publicado: (2020)

CRISPR/Cas9 as a therapeutic tool for triple negative breast cancer: from bench to clinics
por: Tiwari, Prashant Kumar, et al.
Publicado: (2023)

Cytokines and Chemokines in HBV Infection
por: Zhong, Shihong, et al.
Publicado: (2021)

CRISPR-CasRx Targeting LncRNA LINC00341 Inhibits Tumor Cell Growth in vitro and in vivo
por: Li, Chunjing, et al.
Publicado: (2021)

Next-Generation Molecular Diagnostics Development by CRISPR/Cas Tool: Rapid Detection and Surveillance of Viral Disease Outbreaks
por: Srivastava, Sonal, et al.
Publicado: (2020)

Transcriptional Inhibition of lncRNA gadd7 by CRISPR/dCas9-KRAB Protects Spermatocyte Viability
por: Zhao, Jun, et al.
Publicado: (2021)

Engineered CRISPR/Cas13d Sensing hTERT Selectively Inhibits the Progression of Bladder Cancer In Vitro
por: Zhuang, Chengle, et al.
Publicado: (2021)

The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In Vivo
por: Lin, Su-Ru, et al.
Publicado: (2014)

Knockdown of Long Non-coding RNA SNGH3 by CRISPR-dCas9 Inhibits the Progression of Bladder Cancer
por: Cao, Yu, et al.
Publicado: (2021)

A CRISPR-based approach using dead Cas9-sgRNA to detect SARS-CoV-2
por: Aouida, Mustapha, et al.
Publicado: (2023)

Knockdown of LncRNA PANDAR by CRISPR-dCas9 Decreases Proliferation and Increases Apoptosis in Oral Squamous Cell Carcinoma
por: Jia, Tingting, et al.
Publicado: (2021)

Analysis of HBV Genomes Integrated into the Genomes of Human Hepatoma PLC/PRF/5 Cells by HBV Sequence Capture-Based Next-Generation Sequencing
por: Ishii, Tomotaka, et al.
Publicado: (2020)

Up-Regulating ERIC by CRISPR-dCas9-VPR Inhibits Cell Proliferation and Invasion and Promotes Apoptosis in Human Bladder Cancer
por: Yang, Jiangeng, et al.
Publicado: (2021)

Synthetic Artificial Long Non-coding RNA Shows Higher Efficiency in Specific Malignant Phenotype Inhibition Compared to the CRISPR/Cas Systems
por: Yao, Lin, et al.
Publicado: (2020)

CRISPR-Cas13a Targeting the Enhancer RNA-SMAD7e Inhibits Bladder Cancer Development Both in vitro and in vivo
por: Che, Wenan, et al.
Publicado: (2020)

CRISPR-Cas13-Mediated Knockdown of lncRNA-GACAT3 Inhibited Cell Proliferation and Motility, and Induced Apoptosis by Increasing p21, Bax, and E-Cadherin Expression in Bladder Cancer
por: Zhang, Zhongfu, et al.
Publicado: (2021)

Identification of UBE2I as a Novel Biomarker in ccRCC Based on a Large-Scale CRISPR-Cas9 Screening Database and Immunohistochemistry
por: Li, Feng, et al.
Publicado: (2022)

Using CRISPR/Cas9 genome editing in human iPSCs for deciphering the pathogenicity of a novel CCM1 transcription start site deletion
por: Pilz, Robin A., et al.
Publicado: (2022)

Clinical analysis of prolonged viral clearance time in patients with lymphoma combined with novel coronavirus infection
por: Li, Ying, et al.
Publicado: (2023)

lncRNA SNHG9 Promotes Cell Proliferation, Migration, and Invasion in Human Hepatocellular Carcinoma Cells by Increasing GSTP1 Methylation, as Revealed by CRISPR-dCas9
por: Ye, Shanting, et al.
Publicado: (2021)

Regulation of the HBV Entry Receptor NTCP and its Potential in Hepatitis B Treatment
por: Li, Yan, et al.
Publicado: (2022)

Silencing of lncRNA MIR497HG via CRISPR/Cas13d Induces Bladder Cancer Progression Through Promoting the Crosstalk Between Hippo/Yap and TGF-β/Smad Signaling
por: Zhuang, Changshui, et al.
Publicado: (2020)

Corrigendum: Silencing of lncRNA MIR497HG via CRISPR/Cas13d Induces Bladder Cancer Progression Through Promoting the Crosstalk Between Hippo/Yap and TGF-β/Smad Signaling
por: Zhuang, Changshui, et al.
Publicado: (2021)

Identification of a Potential miRNA–mRNA Regulatory Network Associated With the Prognosis of HBV-ACLF
por: Ma, Shanshan, et al.
Publicado: (2021)

Rapid and Sensitive Diagnosis of Drug-Resistant FLT3-F691L Mutation by CRISPR Detection
por: Liu, Yin, et al.
Publicado: (2021)

Corrigendum: Identification of a Potential miRNA-mRNA Regulatory Network Associated With the Prognosis of HBV-ACLF
por: Ma, Shanshan, et al.
Publicado: (2021)

Editorial: Engineering Signal Sensors Based on Reprogrammed CRISPR Technologies
por: Liu, Yuchen, et al.
Publicado: (2021)

Inhibitory Effect of Genistein on PLC/PRF5 Hepatocellular Carcinoma Cell Line
por: Dastjerdi, Mehdi Nikbakht, et al.
Publicado: (2015)

Advances and challenges in CRISPR-based real-time imaging of dynamic genome organization
por: Thuma, Jenna, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2k5tranlln69c1547r6c2bktlb