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Evaluation of the Impact of Intratumoral Heterogeneity of Esophageal Cancer on Pathological Diagnosis and P16 Methylation and the Representativity of Endoscopic Biopsy

BACKGROUND: P16 methylation is expected to be potential diagnostic and therapeutic targets for esophageal cancer (EC). The intratumoral heterogeneity (ITH) of EC has been mentioned but has not been quantitatively measured yet. We aimed to clarify the impact of ITH on pathological diagnosis and P16 m...

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Detalles Bibliográficos
Autores principales: Qin, Yu, Zhou, Jing, Fan, Zhiyuan, Gu, Jianhua, Li, Xinqing, Lin, Dongmei, Deng, Dajun, Wei, Wenqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416173/
https://www.ncbi.nlm.nih.gov/pubmed/34485122
http://dx.doi.org/10.3389/fonc.2021.683876