Structural and Lipidomic Alterations of Striatal Myelin in 16p11.2 Deletion Mouse Model of Autism Spectrum Disorder

Myelin abnormalities have been observed in autism spectrum disorder (ASD). In this study, we seek to discover myelin-related changes in the striatum, a key brain region responsible for core ASD features, using the 16p11.2 deletion (16p11.2(±)) mouse model of ASD. We found downregulated expression of...

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Detalles Bibliográficos
Autores principales: Ju, Jun, Yang, Xiuyan, Jiang, Jian, Wang, Dilong, Zhang, Yumeng, Zhao, Xiaofeng, Fang, Xiaoyi, Liao, Huanquan, Zheng, Lei, Li, Shupeng, Hou, Sheng-Tao, Liang, Liyang, Pan, Yihang, Li, Huiliang, Li, Ningning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416256/
https://www.ncbi.nlm.nih.gov/pubmed/34483844
http://dx.doi.org/10.3389/fncel.2021.718720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416256/
https://www.ncbi.nlm.nih.gov/pubmed/34483844
http://dx.doi.org/10.3389/fncel.2021.718720

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