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Hypermethylation and Downregulation of UTP6 Are Associated With Stemness Properties, Chemoradiotherapy Resistance, and Prognosis in Rectal Cancer: A Co-expression Network Analysis

BACKGROUND: To identify the hub genes associated with chemoradiotherapy resistance in rectal cancer and explore the potential mechanism. METHODS: Weighted gene co-expression network analysis (WGCNA) was performed to identify the gene modules correlated with the chemoradiotherapy resistance of rectal...

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Detalles Bibliográficos
Autores principales: Zhang, Yiyi, Gao, Qiao, Wu, Yong, Peng, Yong, Zhuang, Jinfu, Yang, Yuanfeng, Jiang, Weizhong, Liu, Xing, Guan, Guoxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416280/
https://www.ncbi.nlm.nih.gov/pubmed/34485268
http://dx.doi.org/10.3389/fcell.2021.607782