Indomethacin-based PROTACs as pan-coronavirus antiviral agents

Indomethacin (INM), a well-known non-steroidal anti-inflammatory drug, has recently gained attention for its antiviral activity demonstrated in drug repurposing studies against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Although the mechanism of action of INM is not yet fully unde...

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Detalles Bibliográficos
Autores principales: Desantis, Jenny, Mercorelli, Beatrice, Celegato, Marta, Croci, Federico, Bazzacco, Alessandro, Baroni, Massimo, Siragusa, Lydia, Cruciani, Gabriele, Loregian, Arianna, Goracci, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416298/
https://www.ncbi.nlm.nih.gov/pubmed/34534839
http://dx.doi.org/10.1016/j.ejmech.2021.113814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416298/
https://www.ncbi.nlm.nih.gov/pubmed/34534839
http://dx.doi.org/10.1016/j.ejmech.2021.113814

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