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Indomethacin-based PROTACs as pan-coronavirus antiviral agents
Indomethacin (INM), a well-known non-steroidal anti-inflammatory drug, has recently gained attention for its antiviral activity demonstrated in drug repurposing studies against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Although the mechanism of action of INM is not yet fully unde...
Autores principales: | Desantis, Jenny, Mercorelli, Beatrice, Celegato, Marta, Croci, Federico, Bazzacco, Alessandro, Baroni, Massimo, Siragusa, Lydia, Cruciani, Gabriele, Loregian, Arianna, Goracci, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Masson SAS.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416298/ https://www.ncbi.nlm.nih.gov/pubmed/34534839 http://dx.doi.org/10.1016/j.ejmech.2021.113814 |
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