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Identification of a Novel Inflamed Tumor Microenvironment Signature as a Predictive Biomarker of Bacillus Calmette-Guérin Immunotherapy in Non–Muscle-Invasive Bladder Cancer

PURPOSE: Improved risk stratification and predictive biomarkers of treatment response are needed for non–muscle-invasive bladder cancer (NMIBC). Here we assessed the clinical utility of targeted RNA and DNA molecular profiling in NMIBC. EXPERIMENTAL DESIGN: Gene expression in NMIBC samples was profi...

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Detalles Bibliográficos
Autores principales: Damrauer, Jeffrey S., Roell, Kyle R., Smith, Markia A., Sun, Xuezheng, Kirk, Erin L., Hoadley, Katherine A., Benefield, Halei C., Iyer, Gopakumar, Solit, David B., Milowsky, Matthew I., Kim, William Y., Nielsen, Matthew E., Wobker, Sara E., Dalbagni, Guido, Al-Ahmadie, Hikmat A., Olshan, Andrew F., Bochner, Bernard H., Furberg, Helena, Troester, Melissa A., Pietzak, Eugene J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416390/
https://www.ncbi.nlm.nih.gov/pubmed/34117034
http://dx.doi.org/10.1158/1078-0432.CCR-21-0205