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Predicting Drug-Induced Liver Injury Using Machine Learning on a Diverse Set of Predictors

A major challenge in drug development is safety and toxicity concerns due to drug side effects. One such side effect, drug-induced liver injury (DILI), is considered a primary factor in regulatory clearance. The Critical Assessment of Massive Data Analysis (CAMDA) 2020 CMap Drug Safety Challenge goa...

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Detalles Bibliográficos
Autores principales: Adeluwa, Temidayo, McGregor, Brett A., Guo, Kai, Hur, Junguk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416433/
https://www.ncbi.nlm.nih.gov/pubmed/34483896
http://dx.doi.org/10.3389/fphar.2021.648805