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Novel Butein Derivatives Repress DDX3 Expression by Inhibiting PI3K/AKT Signaling Pathway in MCF-7 and MDA-MB-231 Cell Lines

BACKGROUND: Breast cancer is one of the major causes of mortalities noticed in women globally. DDX3 has emerged as a potent target for several cancers, including breast cancer to which currently there are no reported or approved drugs. METHODS: To find effective cancer therapeutics, three compounds...

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Detalles Bibliográficos
Autores principales: Rampogu, Shailima, Kim, Seong Min, Shaik, Baji, Lee, Gihwan, Kim, Ju Hyun, Kim, Gon Sup, Lee, Keun Woo, Kim, Myeong Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416463/
https://www.ncbi.nlm.nih.gov/pubmed/34485148
http://dx.doi.org/10.3389/fonc.2021.712824