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Novel Butein Derivatives Repress DDX3 Expression by Inhibiting PI3K/AKT Signaling Pathway in MCF-7 and MDA-MB-231 Cell Lines
BACKGROUND: Breast cancer is one of the major causes of mortalities noticed in women globally. DDX3 has emerged as a potent target for several cancers, including breast cancer to which currently there are no reported or approved drugs. METHODS: To find effective cancer therapeutics, three compounds...
Autores principales: | Rampogu, Shailima, Kim, Seong Min, Shaik, Baji, Lee, Gihwan, Kim, Ju Hyun, Kim, Gon Sup, Lee, Keun Woo, Kim, Myeong Ok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416463/ https://www.ncbi.nlm.nih.gov/pubmed/34485148 http://dx.doi.org/10.3389/fonc.2021.712824 |
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