Metformin Alleviates Steatohepatitis in Diet-Induced Obese Mice in a SIRT1-Dependent Way

Metformin is the first-line anti-diabetic drug for type 2 diabetes. It has been found to significantly reduce liver aminotransferase in nonalcoholic fatty liver disease (NAFLD). However, whether metformin improves NAFLD progression remains controversial. Sirtuin 1 (SIRT1), an NAD(+)-dependent deacet...

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Detalles Bibliográficos
Autores principales: Guo, Wan-rong, Liu, Juan, Cheng, Li-dan, Liu, Zi-yu, Zheng, Xiao-bin, Liang, Hua, Xu, Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416468/
https://www.ncbi.nlm.nih.gov/pubmed/34483906
http://dx.doi.org/10.3389/fphar.2021.704112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416468/
https://www.ncbi.nlm.nih.gov/pubmed/34483906
http://dx.doi.org/10.3389/fphar.2021.704112

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