Arginine:Glycine Amidinotransferase Is Essential for Creatine Supply in Mice During Chronic Hypoxia

Objective: Chronic hypoxia induces pulmonary and cardiovascular pathologies, including pulmonary hypertension (PH). L-arginine:glycine amidinotransferase (AGAT) is essential for homoarginine (hArg) and guanidinoacetate synthesis, the latter being converted to creatine by guanidinoacetate methyltrans...

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Detalles Bibliográficos
Autores principales: Hannemann, Juliane, Cordts, Kathrin, Seniuk, Anika, Choe, Chi-un, Schmidt-Hutten, Lena, Duque Escobar, Jorge, Weinberger, Florian, Böger, Rainer, Schwedhelm, Edzard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416470/
https://www.ncbi.nlm.nih.gov/pubmed/34483959
http://dx.doi.org/10.3389/fphys.2021.703069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416470/
https://www.ncbi.nlm.nih.gov/pubmed/34483959
http://dx.doi.org/10.3389/fphys.2021.703069

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