α1-nAchR-Mediated Signaling Through Lipid Raft Is Required for Nicotine-Induced NLRP3 Inflammasome Activation and Nicotine-Accelerated Atherosclerosis

BACKGROUND: Nicotine exerts direct effects on multiple cell types in the cardiovascular system by associating with its high-affinity nicotinic acetylcholine receptors (nAchRs). Lipid raft is a membrane microdomain that recruits various receptors and signaling molecules for coordinating cellular immu...

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Detalles Bibliográficos
Autores principales: Duan, Fengqi, Zeng, Cheng, Liu, Sijun, Gong, Jianfeng, Hu, Jia, Li, Hongyu, Tan, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416509/
https://www.ncbi.nlm.nih.gov/pubmed/34490270
http://dx.doi.org/10.3389/fcell.2021.724699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416509/
https://www.ncbi.nlm.nih.gov/pubmed/34490270
http://dx.doi.org/10.3389/fcell.2021.724699

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