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Downregulation of miR‑214-3p attenuates mesangial hypercellularity by targeting PTEN‑mediated JNK/c-Jun signaling in IgA nephropathy

Mesangial cell (MC) proliferation and matrix expansion are basic pathological characteristics of IgA nephropathy (IgAN). However, the stepwise mechanism of MC proliferation and the exact set of related signaling molecules remain largely unclear. In this study, we found a significant upregulation of...

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Detalles Bibliográficos
Autores principales: Li, Yan, Xia, Ming, Peng, Liang, Liu, Haiyang, Chen, Guochun, Wang, Chang, Yuan, Du, Liu, Yu, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416718/
https://www.ncbi.nlm.nih.gov/pubmed/34512151
http://dx.doi.org/10.7150/ijbs.61274