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Cyclovirobuxine inhibits the progression of clear cell renal cell carcinoma by suppressing the IGFBP3-AKT/STAT3/MAPK-Snail signalling pathway

Of all pathological types of renal cell cancer (RCC), clear cell renal cell carcinoma (ccRCC) has the highest incidence. Cyclovirobuxine (CVB), a triterpenoid alkaloid isolated from Buxus microphylla, exhibits antitumour activity against gastric cancer and breast cancer; however, the mechanism by wh...

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Detalles Bibliográficos
Autores principales: Liu, Yadong, Lv, Huiyan, Li, Xingyi, Liu, Jiannan, Chen, Song, Chen, Yaodong, Jin, Yinshan, An, Ruihua, Yu, Shiliang, Wang, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416721/
https://www.ncbi.nlm.nih.gov/pubmed/34512163
http://dx.doi.org/10.7150/ijbs.62114