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Cyclovirobuxine inhibits the progression of clear cell renal cell carcinoma by suppressing the IGFBP3-AKT/STAT3/MAPK-Snail signalling pathway
Of all pathological types of renal cell cancer (RCC), clear cell renal cell carcinoma (ccRCC) has the highest incidence. Cyclovirobuxine (CVB), a triterpenoid alkaloid isolated from Buxus microphylla, exhibits antitumour activity against gastric cancer and breast cancer; however, the mechanism by wh...
Autores principales: | Liu, Yadong, Lv, Huiyan, Li, Xingyi, Liu, Jiannan, Chen, Song, Chen, Yaodong, Jin, Yinshan, An, Ruihua, Yu, Shiliang, Wang, Zhigang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416721/ https://www.ncbi.nlm.nih.gov/pubmed/34512163 http://dx.doi.org/10.7150/ijbs.62114 |
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