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Pancreatic cancer-derived exosomal microRNA-19a induces β-cell dysfunction by targeting ADCY1 and EPAC2

New-onset diabetes mellitus has a rough correlation with pancreatic cancer (PaC), but the underlying mechanism remains unclear. This study aimed to explore the exosomal microRNAs and their potential role in PaC-induced β-cell dysfunction. The pancreatic β cells were treated with isolated exosomes fr...

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Detalles Bibliográficos
Autores principales: Pang, Wenjing, Yao, Weiyan, Dai, Xin, Zhang, Aisen, Hou, Lidan, Wang, Lei, Wang, Yu, Huang, Xin, Meng, Xiangjun, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416731/
https://www.ncbi.nlm.nih.gov/pubmed/34512170
http://dx.doi.org/10.7150/ijbs.56271