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Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro

Histone deacetylases (HDACs) exhibit increased expression in cancer and promote oncogenesis via the acetylation of or interactions with key transcriptional regulators. HDAC inhibitors (HDACis) decrease HDAC activity to selectively inhibit the occurrence and development of tumors. Our study screened...

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Detalles Bibliográficos
Autores principales: Bai, Miao, Cui, Mengqi, Li, Mingyue, Yao, Xinlei, Wu, Yulun, Zheng, Lihua, Sun, Luguo, Song, Qiuhang, Wang, Shuyue, Liu, Lei, Yu, Chunlei, Huang, Yanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416734/
https://www.ncbi.nlm.nih.gov/pubmed/34512161
http://dx.doi.org/10.7150/ijbs.62339