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NEDD4L-induced β-catenin ubiquitination suppresses the formation and progression of interstitial pulmonary fibrosis via inhibiting the CTHRC1/HIF-1α axis

Interstitial pulmonary fibrosis (IPF) is a severe progressive lung disease with limited therapeutic options and poor prognosis. Initially, we found the downregulated level of neural precursor cell expressed developmentally down-regulated 4-like protein (NEDD4L) in IPF-related expression microarray d...

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Detalles Bibliográficos
Autores principales: Chen, Lin, Yang, Yang, Yan, Haiying, Peng, Xiaying, Zou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416742/
https://www.ncbi.nlm.nih.gov/pubmed/34512149
http://dx.doi.org/10.7150/ijbs.57247