Safety, Tolerability and Pharmacokinetics of the Serotonin 5-HT6 Receptor Antagonist, HEC30654, in Healthy Chinese Subjects

Background and Objective: HEC30654 is a selective 5-HT6 receptor antagonist that was safe and well-tolerated in preclinical models of Alzheimer’s disease. The objective of this double-blind, randomized, placebo-controlled clinical trial was to evaluate the safety, tolerability, and pharmacokinetic p...

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Detalles Bibliográficos
Autores principales: Li, Xiaojiao, Gao, Lei, Liu, Jingrui, Zhang, Hong, Chen, Hong, Yang, Lizi, Wu, Min, Li, Cuiyun, Zhu, Xiaoxue, Ding, Yanhua, Sun, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416768/
https://www.ncbi.nlm.nih.gov/pubmed/34489712
http://dx.doi.org/10.3389/fphar.2021.726536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416768/
https://www.ncbi.nlm.nih.gov/pubmed/34489712
http://dx.doi.org/10.3389/fphar.2021.726536

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