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Effect of Oral Semaglutide on the Pharmacokinetics of Levonorgestrel and Ethinylestradiol in Healthy Postmenopausal Women and Furosemide and Rosuvastatin in Healthy Subjects
BACKGROUND: The first oral glucagon-like peptide-1 receptor agonist (GLP-1RA) comprises semaglutide co-formulated with the absorption enhancer, sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC). Oral semaglutide may alter the pharmacokinetics of co-administered drugs via effects of semaglutide...
Autores principales: | Jordy, Andreas B., Albayaty, Muna, Breitschaft, Astrid, Anderson, Thomas W., Christiansen, Erik, Houshmand-Øregaard, Azadeh, Manigandan, Easwaran, Bækdal, Tine A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416862/ https://www.ncbi.nlm.nih.gov/pubmed/33782832 http://dx.doi.org/10.1007/s40262-020-00976-x |
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