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Population Pharmacokinetics and Pharmacodynamics of Once-Daily Growth Hormone Norditropin(®) in Children and Adults

BACKGROUND AND OBJECTIVE: Once-daily injectable recombinant human growth hormone (GH) formulations (e.g. Norditropin(®); Novo Nordisk A/S) are used to treat GH deficiency in children and adults, with much of the therapeutic effect mediated via the insulin-like growth factor-I (IGF-I) response. Despi...

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Detalles Bibliográficos
Autores principales: Papathanasiou, Theodoros, Agersø, Henrik, Damholt, Birgitte Bentz, Højby Rasmussen, Michael, Kildemoes, Rasmus Juul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416863/
https://www.ncbi.nlm.nih.gov/pubmed/33864240
http://dx.doi.org/10.1007/s40262-021-01011-3