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Memory-like Differentiation Enhances NK Cell Responses to Melanoma
PURPOSE: Treatment of advanced melanoma is a clinical challenge. Natural killer (NK) cells are a promising cellular therapy for T cell–refractory cancers, but are frequently deficient or dysfunctional in patients with melanoma. Thus, new strategies are needed to enhance NK-cell antitumor responses....
Autores principales: | Marin, Nancy D., Krasnick, Bradley A., Becker-Hapak, Michelle, Conant, Leah, Goedegebuure, Simon P., Berrien-Elliott, Melissa M., Robbins, Keenan J., Foltz, Jennifer A., Foster, Mark, Wong, Pamela, Cubitt, Celia C., Tran, Jennifer, Wetzel, Christopher B., Jacobs, Miriam, Zhou, Alice Y., Russler-Germain, David, Marsala, Lynne, Schappe, Timothy, Fields, Ryan C., Fehniger, Todd A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416927/ https://www.ncbi.nlm.nih.gov/pubmed/34187852 http://dx.doi.org/10.1158/1078-0432.CCR-21-0851 |
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