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Development of a Novel Mouse Model of Spontaneous High-Risk HPVE6/E7–Expressing Carcinoma in the Cervicovaginal Tract

Current preclinical models for cervical cancer lack important clinical and pathologic features. To improve upon these models, we aimed to develop a novel, spontaneous HPV16-expressing carcinoma model that captures major aspects of HPV-associated cancer in the female genital tract. This novel preclin...

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Detalles Bibliográficos
Autores principales: Henkle, Talia R., Lam, Brandon, Kung, Yu Jui, Lin, John, Tseng, Ssu-Hsueh, Ferrall, Louise, Xing, Deyin, Hung, Chien-Fu, Wu, T.-C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416934/
https://www.ncbi.nlm.nih.gov/pubmed/34215618
http://dx.doi.org/10.1158/0008-5472.CAN-21-0399