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Extended disorder at the cell surface: The conformational landscape of the ectodomains of syndecans

Syndecans are membrane proteoglycans regulating extracellular matrix assembly, cell adhesion and signaling. Their ectodomains can be shed from the cell surface, and act as paracrine and autocrine effectors or as competitors of full-length syndecans. We report the first biophysical characterization o...

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Detalles Bibliográficos
Autores principales: Gondelaud, Frank, Bouakil, Mathilde, Le Fèvre, Aurélien, Miele, Adriana Erica, Chirot, Fabien, Duclos, Bertrand, Liwo, Adam, Ricard-Blum, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416954/
https://www.ncbi.nlm.nih.gov/pubmed/34505054
http://dx.doi.org/10.1016/j.mbplus.2021.100081