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Fibroblast Activation Protein-α as a Target in the Bench-to-Bedside Diagnosis and Treatment of Tumors: A Narrative Review

Fibroblast activation protein-α (FAP) is a type II integral serine protease that is specifically expressed by activated fibroblasts. Cancer-associated fibroblasts (CAFs) in the tumor stroma have an abundant and stable expression of FAP, which plays an important role in promoting tumor growth, invasi...

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Detalles Bibliográficos
Autores principales: Xin, Lei, Gao, Jinfang, Zheng, Ziliang, Chen, Yiyou, Lv, Shuxin, Zhao, Zhikai, Yu, Chunhai, Yang, Xiaotang, Zhang, Ruiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416977/
https://www.ncbi.nlm.nih.gov/pubmed/34490078
http://dx.doi.org/10.3389/fonc.2021.648187