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Telomere Shortening in Peripheral Leukocytes Is Associated With Poor Survival in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy

BACKGROUND: Immune checkpoint inhibitor (ICI) therapy represents a new standard of care for an increasing number of malignancies. Nevertheless, response rates and outcome of ICI treatment vary between individuals and the identification of predictive markers or hints towards immune cell exhaustion du...

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Detalles Bibliográficos
Autores principales: Rolles, Benjamin, Gorgulho, Joao, Tometten, Mareike, Roderburg, Christoph, Vieri, Margherita, Abels, Anne, Vucur, Mihael, Heymann, Felix, Tacke, Frank, Brümmendorf, Tim H., Luedde, Tom, Beier, Fabian, Loosen, Sven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417059/
https://www.ncbi.nlm.nih.gov/pubmed/34490122
http://dx.doi.org/10.3389/fonc.2021.729207